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2006 Summer Program on Multiplicity and Reproducibility in Scientific Studies

Kickoff Workshop

July 10-12, 2006
at the Radisson Hotel RTP

General Information
Application
Schedule

General Information

The Kickoff Workshop will be held July 10-12, 2006, and will focus on clear formulation of the challenges in the area, especially the issues of reproducibility of scientific experiments, massive multiple testing, and subgroup analysis. The workshop will set the stage for the subsequent Program research, through tutorials, talks and discussion sessions designed to focus attention on the key problems to be considered by the program working groups.

Program Committee: Peter Mueller (M.D. Anderson Cancer Center), Juliet Shaffer (Univ. of California - Berkeley), Peter Westfall (Texas Tech. University, Chair), Stan Young (NISS, Local Scientific Coordinator).

Application

On-line registration for the Kickoff Workshop for the 2006 Summer Program on Multiplicity and Reproducibility in Scientific Studies is now closed.

You may register on-site at Monday, July 10, 2006 at the Radisson Hotel RTP.

Schedule


Monday, July 10, 2006s
Radisson Hotel RTP

8:15-9:10 Registration and Continental Breakfast
9:10-9:30 Welcome, Jim Berger and Stan Young
9:30-12:00 False Discovery and Multiple Comparisons

9:30-10:30 False Discovery Control
Larry Wasserman, Carnegie-Mellon University
10:30-11:00
 Break
11:00-12:00 Inferences on the Proportion of non-Null Effects in Large-scale Multiple Comparisons
Jiashun Jin, Purdue University
12:00-1:15 Lunch
1:15-3:15 Subgroup Analysis and High Dimensional Data

1:15-2:15 Identifying Meaningful Patient Subgroups via Clustering - Sensitivity Graphics
Robert Obenchain, Eli Lilly and Company
2:15-3:15 Large p Small n Asymptotics for Statistical Analysis of High Dimensional Data
Michael Kosorok, UNC-Chapel Hill
3:15-3:45 Break
3:45-4:45 View from the Food and Drug Administration
Bob O'Neill - Director of Biostatistics, FDA
Comment from Telba Irony - Center for Devices
4:45-5:15 Poster Session Advertisements
6:30-8:30 Poster Session (abstracts)

SAMSI will provide poster presentation boards and tape. The board dimensions are 4 ft. wide by 3 ft. high. They are tri-fold with each side being 1 ft. wide and the center 2 ft. wide. Please make sure your poster fits the board. The boards can accommodate up to 16 pages of paper measuring 8.5 inches by 11 inches.

Tuesday, July 11, 2006
Radisson Hotel RTP

8:30-9:00 Registration and Continental Breakfast
9:00-12:15 Multiplicity and Reproducibility

9:00-10:00 Multiplicities: Minefields for Bayesians
Don Berry, M.D. Anderson Cancer Center
10:00-11:00 Generalizing Some FWER and FDR Procedures
Sanat Sarkar, Temple University
11:00-11:15 Break
11:15-12:15 The Role of FDR Based Inference in Ensuring Reproducible Results
Dani Yekutieli, Tel Aviv University
12:15-1:30 Lunch
1:30-3:30 Multiplicity in Genomics

1:30-2:30 Statistical Methods for Expression Quantitative Trait Loci Mapping
Christina Kendziorski, Univ. of Wisconsin-Madison
2:30-3:30 On Enrichment of a Gene Category for Altered Genes
Michael Newton, Univ. of Wisconsin-Madison
3:30-4:00 Break
4:00-5:20 New Researchers Session

Jing Qiu, University of Missouri Sharp Simultaneous Intervals for the Means of Selected Populations with Application to Microarray Data Analysis
Ken Rice, University of Washington Connections Between Local FDR and Alternative Hypotheses
Lei Sun, University of Toronto Some multiplicity and reproducibility problems in genome-wide genetic studies

Wednesday, July 12, 2006
Radisson Hotel RTP

8:30-9:00 Continental Breakfast
9:00-11:00 Bayesian Views of Multiple Testing

9:00-10:00 A Bayesian Approach to the Estimation of False Discovery Rates
Subhashis Ghosal, N.C. State University
10:00-11:00 Multiple Testing: Some Contrasts Between Frequentist and Bayesian Approaches
Susie Bayarri, University of Valencia
11:00-11:15 Break
11:15-12:15 Modeling Dependence for High-Throughput Multivariable Experiments
Peter Hoff, University of Washington
12:15-1:15 Lunch
1:15-2:30 Discussion of Working Group on Multiplicity
Peter Mueller (Moderator) - M.D. Anderson Cancer Center, Telba Irony - FDA, Helmut Finner - German Diabetes Center
2:30-3:45 Discussion of Working Group on Subgroup Analysis:
Juliet Shaffer (Moderator) - Univ. of California-Berkeley, Alok Krishen - GlaxoSmithKline, Gary Rosner - M.D. Anderson Cancer Center, S. Sivaganesan- Univ. of Cincinnati
3:45-4:15 Break
4:15-5:30 Discussion of Working Group on Replicability:
Stan Young (Moderator), Steve Goodman - Johns Hopkins University, Valen Johnson - M.D. Anderson Cancer Center

 




 
 

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