Fall 2019 Postdoc Seminar Series
October 30, 2019 –
Talk Title: Experimental Design in Genomics
Speaker: Bianca Dumitrascu, First-Year SAMSI Postdoctoral Fellow
The traditional biological research pipeline consists of three steps: hypothesis generation, data collection, and data analysis. Data analysis is sometimes followed by a readjustment in hypothesis assessment, allowing for an iterative approach to the scientific inquiry. With the decreasing costs of data collection in high-throughput genomics, and with the increasing number of groups pursuing interconnected questions, several experimental design challenges emerge. In this work, we address three experimental challenges motivated by advances in single-cell RNA-seq (scRNA-seq) technologies: budget allocation, marker selection and multi-modal data aggregation.
No references provided at this time