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2008-09 Program on Algebraic Methods in Systems Biology and Statistics

Tutorials and Opening Workshop

September 14-17, 2008

General Information
Application
Schedule

General Information

The Opening Workshop for the SAMSI program on Algebraic Methods in Systems Biology and Statistics will be held on Sunday-Wednesday, September 14-17, 2008, at the Radisson Hotel RTP in Research Triangle Park, NC. On Sunday, September 14, tutorials will be offered on various applications of algebra in biology and statistics. From Monday to Wednesday, invited speakers will give presentations. We will also have a poster session.

The goals of the Opening Workshop are to take advantage of community input in the formation of the working groups for the program and to promote engagement in person or remotely, via web or teleconference for those not in residence at SAMSI during the program.

The workshop program will focus on the development and use of a particular set of tools from algebra, algebraic geometry, and discrete mathematics to solve problems in statistics and biology. A fundamental component of the workshop will take place during the afternoon of Wednesday, September 17, with the formation of working groups who will pursue research during the remainder of the program.

Program Committee: Reinhard Laubenbacher (Virginia Tech: Chair), Seth Sullivant (North Carolina State University), Brett Tyler (Virginia Tech), Rudy Yoshida (University of Kentucky)

Application

The on-line application process is now closed.

Schedule

Sunday, September 14, 2008
Radisson Hotel RTP

Overview Tutorials

11:15-Noon Registration
12:00-1:00 Lunch
1:00-2:15 An Invitation to Algebraic Statistics
Homework Assignment
Bernd Sturmfels, University of California, Berkeley
2:15-2:30 Break
2:30-3:45 An Introduction to Systems Biology
Reinhard Laubenbacher, Virginia Bioinformatics Institute
3:45-4:00 Break
4:00-5:15 Phylogenetics
Elizabeth Allman, University of Alaska

Monday, September 15, 2008
Radisson Hotel RTP

8:00-8:45 Registration and Continental Breakfast
8:45-9:00 Welcome
9:00-9:45 Algebraic Statistical Models
Mathias Drton, University of Chicago
9:45-10:00 Questions and Discussions
10:00-10:45 The Geometry of Multisite Phosphorylation
Jeremey Gunawardena, Harvard University
10:45-11:00 Questions and Discussions
11:00-11:15 Coffee Break
11:15-Noon Combinatorial Insights into RNA Folding
Christine Heitsch, Georgia Institute of Technology
Noon-12:15 Questions and Discussions
12:15-1:30 Lunch
1:30-2:15 Algebra, Automata, Algorithms, Biology and Beyond
Bud Mishra, Courant Institute, New York University
2:15-2:30 Questions and Discussions
2:30-3:15 Reverse Engineering Nested Canalyzing Boolean Networks
Abdul Jarrah, Virginia Bioinformatics Institute
3:15-3:30 Questions and Discussions
3:30-3:45 Break
3:45-4:30 Species and Genomes: Lessons from my Favorite Symbionts
Chris Schardl, University of Kentucky
4:30-4:45 Questions and Discussions
4:45-6:00 Panel Discussion:
Jeremy Gunawardena, Harvard University
Ina Hoeschele, Virginia Polytechnic Institute
Alexander Hartemink, Duke University
Greg Rempala, Medical College of Georgia
Brett Tyler, Virginia Polytechnic Institute
6:00-6:30 Poster Advertisement Session (2 minute ads each)
6:30-8:30 Poster Session and Reception

SAMSI will provide poster presentation boards and tape. The board dimensions are 4 ft. wide by 3 ft. high. They are tri-fold with each side being 1 ft. wide and the center 2 ft. wide. Please make sure your poster fits the board. The boards can accommodate up to 16 pages of paper measuring 8.5 inches by 11 inches.

Tuesday, September 16, 2008
Radisson Hotel RTP

8:15-9:00 Registration and Continental Breakfast
9:00-9:45 Algebraic Structure of System Design Space for Metabolic Pathways and Gene Circuits
Michael Savageau, University of California, Davis
9:45-10:00 Questions and Discussions
10:00-10:45 Polynomial Equations and Instabilities in Biochemical Reaction Networks
Gheorghe Craciun, University of Wisconsin
10:45-11:00 Questions and Discussions
11:00-11:15 Coffee Break
11:15-Noon Algebraic Geometry, Empirical Process, and Singular Model Evaluation
Sumio Watanabe, Tokyo Institute of Technology
Noon-12:15 Questions and Discussions
12:15-1:30 Lunch
1:30-2:15 Using Gröbner Bases to Reconstruct Regulatory Models in C. elegans
Brandy Stigler, Mathematical Biosciences Institute
2:15-2:30 Questions and Discussions
2:30-3:15 Algebraic Combinatorics for Predicting Virus Assembly Pathways
Meera Sitharam, University of Florida
3:15-3:30 Questions and Discussions
3:30-3:45 Break
3:45-4:30 The Algebra and Statistics of Biological Sequence Alignment
Lior Pachter, Univ. of California-Berkeley
4:30-4:45 Questions and Discussions
4:45-6:00 Panel Discussion:
Bernd Sturmfels, University of California, Berkeley
Seth Sullivant, North Carolina State University
Rudy Yoshida, University of Kentucky
Peter Beerli, Florida State University
Elizabeth Allman, University of Alaska

Wednesday, September 17, 2008
Radisson Hotel RTP

8:15-9:00 Registration and Continental Breakfast
9:00-9:45 Inferring Genetic Regulatory Networks in Host-Pathogen Interactions
Brett Tyler, Virginia Polytechnic University
9:45-10:00 Questions and Discussions
10:00-10:45 Mathematical Models of Evolutionary Escape
Niko Beerenwinkel, ETH Zurich
10:45-11:00 Questions and Discussions
11:00-11:15 Coffee Break
11:15-Noon Classes of Discrete Causal Models
Eva Riccomagno, Università di Genova
Noon-12:15 Questions and Discussions
12:15-1:30 Lunch
1:30-2:15 Algebraic Statistics for p1 Random Graph Models: Markov Bases and Their Uses
Stephen Fienberg, Carnegie Mellon University
2:15-2:30 Questions and Discussions
2:30-2:45 Break
2:45-5:00 Break-out Sessions for Working Groups

(Thursday and Friday: Possible working group meetings at SAMSI.)

 




 
 

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