2014-15: Bioinformatics: Transition Workshop: May 11-13, 2015

Workshop Information

May 11, 2015 - 8:30am - May 13, 2015 - 12:30pm

Schedule
Participant List
Speaker Titles & Abstracts
Posters

Description

This final, transition workshop for the Beyond Bioinformatics program is designed as an opportunity for the active working groups in the 2014-15 research program to present the work of their groups. In contrast to the Opening Workshop where the focus was on overview talks and talks that emphasized open problems in various areas of bioinformatics, this workshop will be narrower in focus, only emphasizing the research progress that was made since early Fall 2014 in the program’s working groups. Talks that present research that is in progress or research that was completed as a consequence of the SAMSI program will be emphasized. This will also be an opportunity to showcase research by post-doctoral associates and graduate students who were active in the program. Finally, the workshop will be designed to enable working group leaders and participants to plan for research collaborations beyond the active time period of the SAMSI research program.

SAMSI Directorate Liaison: Sujit Ghosh, NCSU & SAMSI

If you have any questions please send email to [email protected]

Schedule

Monday, May 11, 2015
at SAMSI

8:30-9:15 a.m. Registration
9:15 - 9:30 Introduction and Welcome
Sujit Ghosh, SAMSI & N.C. State University
9:30-10:00 Session 1: Program Overview and Updates
Chair: Snehalata Huzurbazar, University of Wyoming
10:00-10:15 Break
  Session 2: Microbial Community Dynamics and Complexity
Chair: Snehalata Huzurbazar, University of Wyoming
10:15-10:35 Alexander Alekseyenko, NYU School of Medicine
Update on Microbial Interaction Inference Methodology Working Group
10:35-10:55 Paul Brooks, Virginia Commonwealth University
The Microbiome and Women's Health
10:55-11:15 Georg Gerber, Harvard University
Bayesian Inference of Dynamical Systems Models from Microbiome Time-Series Data
11:15-11:35 Liyang Diao, Yale University
Pitfalls in Microbiome Differential Abundance Analysis using Current RNA-Seq Processing Methods
11:35-11:55 Katia Smirnova, University of Wyoming
Microbiome Normalization Methods: Effect on Ordination Analysis
11:55-12:00 Group Photo
12:00-1:30 Lunch
  Session 3: Next Generation Sequencing Errors
Chair: Xinping Cui, University of California, Riverside
1:30-1:40 Karin Dorman, Iowa State University
Overview of NGS Errors Working Group
1:40-2:20 Ashley Cacho, University of California, Riverside
A Survey of Base-calling Algorithms for Illumina Sequencing Technology
2:20-3:00 Xin Yin, Iowa State University
PREMIER-bc: Integrated Base-Calling and Error-Correction Approach Using Hidden Markov Model
3:00-3:15 Break
  Session 4: Whole Genome Methylation and Chromatin Interaction
Chairs: Shili Lin, Ohio State University and Steve Qin, Emory University
3:15-3:45 Shili Lin, Ohio State University and Steve Qin, Emory University
Statistical Challenges in Analyzing Methylation and Long-Range Interaction Data
3:45-4:15 Ben Li, Emory University
Comparative Analyses of Whole Genome Bisulphite Sequencing Data Across Multiple Cell Types and Species
4:15-4:45 Deepak Ayyala, Ohio State University
3D Chromatin Reconstruction using TAD-Penalized Models
5:00 Dinner on your own

Tuesday, May 12, 2015
at SAMSI

8:30-8:45 a.m. Registration
8:45-9:00 Introduction
Snehalata Huzurbazar, University of Wyoming
  Session 5: Data Integration: TCGA
Chairs: Ronglai Shen, Memorial Sloan Kettering Cancer Center
Veera Baladandayuthapani, UT MD Anderson Cancer Center
9:00-9:30 Elizabeth McGuffey, UT MD Anderson Cancer Center
piBAG: Pathway Based Integrative Analysis of Multiplatform Genomics Data
9:30-9:50 Yuping Zhang, University of Connecticut
Leveraging Multiple Omics Data to Infer Pathway Disturbance in Complex Diseases
9:50-10:10 Bin Zhu, National Cancer Institute and Ronglai Shen, Memorial Sloan Kettering Cancer Center
Integrating Clinical and Molecular Data for Survival Prediction in TCGA
10:10-10:30 Break
  Session 6: Data Integration: COPD
Chairs: Katerina Kechris, CU Denver, and Hongyu Zhao, Yale University
10:30-11:00 Katerina Kechris (Intro), CU Denver
New Directions in Data Integration using Chronic Obstructive Pulmonary Disease (COPD) as a Case Study
11:00-11:30 Qiongshi Lu, Yale University
Post-GWAS Prioritization through Integrated Analysis of Genomic Functional Annotation
11:30-12:00 Jeihuan Sun, Yale University
Discovery of Novel Loci Associated with COPD by Pooling Information from Related Clinical Feature and Functional Annotation
12:00-1:30 Lunch
  Session 7: Analysis of High-dimensional Discrete Data
Chair: Fei Zou, UNC-Chapel Hill
1:30-2:00 Jyotishka Dutta, SAMSI and Duke University
Multiscale Bayesian Cluster Detection and Testing for Whole Genome Sequencing Studies
2:00-2:30 Yumou Qiu, University of Nebraska-Lincoln
Thresholding Tests for Signal Detection on High-dimensional Count Distributions
2:30-3:00 Fei Zou, UNC-Chapel Hill
Allelic-Specific Gene Expression and Quantitative Trait Analysis
3:00-3:15 Break
  Session 8: Multiple Hypothesis Testing and Simultaneous Inference
Chair: Fred Wright, N.C. State University
3:15-3:45 Fred Wright, N.C. State University
Update on the Multiple Hypothesis Testing Working Group
3:45-4:15 Yihui Zhou, N.C. State University
The Moment Corrected Correlation Method for High Dimensional Data
4:15-4:45 Pratyaydipta Rudra, UNC-Chapel Hill
A Procedure to Detect General Association Based on Concentration of Ranks
4:45-5:30 Break
5:30-7:00 Poster Session and Reception

SAMSI will provide poster presentation boards and tape. The board dimensions are 4 ft. wide by 3 ft. high. They are tri-fold with each side being 1 ft. wide and the center 2 ft. wide. Please make sure your poster fits the board. The boards can accommodate up to 16 pages of paper measuring 8.5 inches by 11 inches.

Wednesday, May 13, 2015
at SAMSI

8:30-8:45 a.m. Registration
8:45-9:00 Introduction
Snehalata Huzurbazar, University of Wyoming
 : Session 9: Imaging Genetics
Chair: Hongtu Zhu, UNC-Chapel Hill
9:00-9:30 Wei Pan, University of Minnesota
Approximate Score-Based Testing with Application to Multivariate Trait Association Analysis
9:30-10:00 Yize Zhao, SAMSI and UNC-Chapel Hill
Bayesian Hierarchical Variable Selection for Genome-wide Association Studies
10:00-10:30 Tian Ge, MGH, Harvard Medical School
Probing the Genetic Underpinnings of Structural Neuroimaging Phenotypes
10:30-10:45 Break
  Session 10: Dependence in Evolutionary Models
Chair: Seth Sullivant, N.C. State University
10:45-11:15 Scott Schmidler, Duke University
Incorporating Dependence into Evolutionary Models for Protein Structure Alignment
11:15-11:45 Jotun Hein, Oxford University
Models of Gene Duplications
11:45-12:15 Jeff Thorne, N.C. State University
Evolutionary Inference with Interlocus Gene Conversion
12:15-12:30 Concluding Remarks
12:30 Box lunch and Adjourn