2014-15: Bioinformatics: Statistical and Computational Challenges in Omics Data Integration (SCC-ODI): February 16-17, 2015
Workshop Information
Schedule
Participant List
Speakers Titles Abstracts
Posters
This workshop was held at SAMSI in Research Triangle Park, NC.
Description: The focus of the workshop was to examine the statistical and computational challenges arising from the analysis and interpretation of diverse types of omics data (genomics, proteomics, genetics, etc). The workshop featured current and ongoing research work by two working groups within the Beyond Bioinformatics program. The Cancer Genome Atlas (TCGA) group is exploring the inference of cancer subtypes, and multidimensional outcome predictions through the joint analysis of diverse data types. The Chronic Obstructive Pulmonary Disease (COPD) working group is exploring the biological problems that include studying multivariate disease phenotypes, using omic data for sub-type identi cation, in depth exploration of GWAS results and identifying pathways associated with disease. Statistical tools explored in the working groups include graphical models, kernel machines, unsupervised learning, survival prediction, and pathway and network analysis. One of the main purposes of this mid-program workshop is for the two working groups to meet and discuss common approaches, present updates and interact face-to-face. The target audience was the regular working group participants which include a mix of students, post-doctoral fellows and junior and senior faculty.
Participants optionally submitted an abstract for a short presentation at a Poster session held on Monday (Feb 16th, 2015) evening. A small subset of the submitted abstracts were selected for short presentations at the workshop.
SAMSI Directorate Liaison: Sujit Ghosh
If you have any questions please send email to [email protected]
Schedule
Monday, February 16, 2015
at SAMSI
| 8:00-8:30 a.m. | Registration |
| 8:30-8:45 | Introduction and Welcome - Sujit Ghosh, SAMSI and Katerina Kechris, University of Colorado Denver |
| Session 1 Chair: Ronglai Shen, Memorial Sloan Kettering Cancer Center |
|
| 8:45-9:30 | Yufeng Liu, University of North Carolina Sparse Regression Incorporating Graphical Structure Among Predictors |
| 9:30-10:00 | Alberto Cassese, Rice University A Bayesian Model for the Identification of Differentially Expressed Genes in Daphnia Magna Exposed to Munition Pollutants |
| 10:00-10:30 | Break |
| Session 2 Chair: Hongyu Zhao, Yale University |
|
| 10:30-11:00 | Xiting Yan , Yale University Identifying Disease Heterogeneity from Gene Expression Data by Integrating Pathway Information |
| 11:00-11:30 | Francesco Stingo, MD Anderson Cancer Center A Bayesian Approach to Biomarker Selection through miRNA Regulatory Networks |
| 11:30-12:00 | Sandra Safo, Emory University Sparse Analysis of High Dimensional Data with Application to Data Integration |
| 12:00-12:30 | Ali Shojaie, University of Washington Network-Based Pathway Enrichment Analysis of Omics Data |
| 12:30-1:30 | Lunch |
| Session 3: Working Group Updates Chair: Katerina Kechris, University of Colorado Denver |
|
| 1:30-2:00 | Bin Zhu, NCI Integrating Clinical and Molecular Data for Survival Prediction in TCGA |
| 2:00-2:30 | Junxiao Hu, University of Colorado - Denver Exploratory Study of Gene Expression in COPD Using Network Analysis and Kernel Machine Methods |
| 2:30-3:00 | Jiehuan Sun, Yale University Discovery of Novel Loci Associated with COPD by Pulling Information from Case-control status, Related Clinical Feature, and Functional Annotation |
| 3:00-3:30 | Qiongshi Lu, Yale University Post-GWAS Prioritization Through Integrated Analysis of Functional Annotation |
| 3:30-4:00 | Break |
| Session 4: Keynote Talk Chair: Veera Baladandayuthapani, MD Anderson Cancer Center |
|
| 4:00-5:00 | Keynote Speaker Keith Baggerly, MD Anderson Cancer Center Integrating Data, Assays, and Pathways: The 20,000 Foot View |
| 5:00-7:00 | Poster Session and Reception SAMSI will provide poster presentation boards and tape. The board dimensions are 4 ft. wide by 3 ft. high. They are tri-fold with each side being 1 ft. wide and the center 2 ft. wide. Please make sure your poster fits the board. The boards can accommodate up to 16 pages of paper measuring 8.5 inches by 11 inches. |
Tuesday, February 17, 2015
at SAMSI
| 8:30-8:45 | Registration and Announcements, Katerina Kechris, University of Colorado Denver |
| 8:45-10:30 | TCGA and COPD Working Group Breakout Sessions SAMSI Room 150 NISS Room 104 |
| 10:30 | Adjourn |