19 T.W. Alexander Drive P.O.Box 14006 Research Triangle Park, NC 27709-4006 Tel: 919.685.9350 Fax: 919.685.9360 [email protected]

Reproducibility
A Working Group in Multiplicity and Reproducibility in Scientific Studies

Group Leaders: Stan Young (National Institute of Statistical Sciences)

Password Protected Site (future)

Announcements

Meeting Time: Daily 3:00 - 4:45, July 13 - 26, 2006
Location: NISS building, 2nd floor conference room

Remote access for the meeting is available:
Via teleconference at 919-685-9338

Note: Until we can get the needed bandwidth, equipment, etc. for broadcasting meetings via a webcam, SAMSI will be employing the following process for remote participation in working groups. A webcam picture will be available for viewing during the meetings. However, for audio, participants will have to call into the conference line.

Meeting Activities

Date	Topics & Readings	Notes
July 13, 2006	Reproducibility Working Group, Meeting 1, 13 July 2006 (summary)	Reproducibility Data File in Excel (file)
July 14, 2006	Presentation by Keith O'Rourke, Ottawa Health Research Institute (zip)	Papers: Benson and Hartz article 2002 (pdf), Concato et al article 2000 (pdf), LeLorier et al article 1997 (pdf), Subgroup analysis article from Lancet 2005 (pdf)
July 17, 2006		op-ed piece on scientific fraud
July 18, 2006
July 19, 2006	Continuation of presentation by Yoav Benjamini, Tel Aviv University: "Some thoughts on Replicability Issues in Science" (Abstract) (Slides)
July 20, 2006		Genetics Editorial (pdf)
July 21, 2006
July 24, 2006
July 25, 2006	Reproducibility Working Group Summary of Topics July 25, 2006 (Summary)  Notes from Reproducibility Working Group Meeting July 25, 2006 (Notes)
July 26, 2006	Presentation by Ramin Arani, Bristol-Myers Squibb Company: “Safety Data Mining: Background and Current Issues” (Slides)
July 27, 2006	Some notes on reproducibility (Notes)
July 28, 2006	Transition Workshop Day 10:00 - 10:45 “Adaptive Hypothesis Testing Intervals: a Calibration of p-values for Large Samples” Luis Pericchi, University of Puerto Rico, Rio Piedras 10:45 – 11:30 “Subgroup Analysis - a Stylized Bayes Approach” Siva Sivaganesan, University of Cincinnati 11:45 - 12:15 Comments from the Subgroup Analysis Working Group Juliet Shaffer, University of California-Berkeley 12:15-13:00 Comments from the Reproducibility Working Group Stan Young, NISS and Bob Obenchain, Eli Lilly and Company 13:00 - 14:00 Lunch 14:00 Final discussion, Open floor

Group Members

Name	Affiliation	Email Address
Ramin Arani	Bristol-Myers Squibb Company	[email protected]
Jim Berger	SAMSI	[email protected]
Valen Johnson	University of Texas M.D. Anderson Cancer Center	[email protected]
Delong Liu	CIIT Centers for Health Research	[email protected]
Bob Obenchain	Eli Lilly and Company	[email protected]
Keith O'Rourke	Ottawa Health Research Institute	[email protected]
James Scott	Duke University	[email protected]
Juliet Shaffer	University of California-Berkeley	[email protected]
Lei Sun	University of Toronto	[email protected]
Rochelle Tractenberg	Georgetown University School of Medicine	[email protected]
David Umbach	National Institute of Environmental Heath Sciences	[email protected]
Stan Young	National Institute of Statistical Sciences	[email protected]
David Siroky	Duke University	[email protected]
Prakash Laud	Medical College of Wisconsin, Division of Biostatistics	[email protected]
Marianthi Markatou	Department of Biostatistics, Columbia University	[email protected]

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