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Statistical and Applied Mathematical Sciences Institute
19 T.
W. Alexander Drive
P.O. Box 14006
Research Triangle Park, NC
27709-4006
Tel: 919.685.9350 FAX: 919.685.9360
[email protected]
Collective Computational Biology for Infectious Disease
Genomes to Global Health: Computational Biology of Infectious Diseases
Closing Workshop
May 22-24, 2005
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GENERAL INFORMATION
Summary
We are convening a
three-day workshop to explore novel approaches to the amelioration of infectious
disease in the developing world through collective, open source and public
efforts in computational biology and informatics.
We will gather experts to help identify those scientific problems and
approaches most susceptible to these methods, and the organization of public resources, the coordination of
collective research efforts, and the dissemination of educational materials to
address these critical problems. Our
ultimate goal is to speed the development of drugs, vaccines and other
therapeutic and prophylactic interventions where financial and market-based
incentives are unlikely to lead to the desired results.
The meeting will
consist of two days of working sessions and a one-day public symposium.
Background
The completion of
the human genome project promises to usher in a new era of biomedical
advancement, but the path from genome sequence to disease cure is complex and
will require significant contributions from the mathematical and information
sciences for its illumination. The
time, energy and financial resources required to turn DNA sequences into disease
cures is now invested most heavily into projects with high probability of
monetary reward�cardio-vascular disease, cancer, and aging, for example.
Infectious disease remains a major cause of premature death worldwide,
but brings suffering disproportionately to people in the developing world.
Relief from the scourges of malaria, schistosomiasis and leishmaniasis,
for example, will not soon flow from market forces alone.
The open source movement in software development provides a powerful paradigm for harnessing the power of collective intelligence for the solution of complex practical problems. We believe that infectious disease genomics can be effectively studied and utilized for the development of drugs and vaccines using similar methods. There will be, however, significant challenges. These challenges involve many social and legal issues, such as intellectual property rights, the appropriate assignment of credit and recognition for successes, the coordination of efforts, quality control and financial support.
Our intent during this three day meeting is to determine the key scientific questions and research opportunities as well as the social, legal and policy challenges and develop strategies to address them. This is necessarily a broadly interdisciplinary effort. We seek to enlist the participation of key members of the scientific and medical communities as well as of the genomics, bioinformatics, computing and mathematical sciences communities to help lead the effort.
Organizers
Tom Kepler and
Lindsay Cowell (Duke University Laboratory of
Computational Immunology)
Arti Rai, Stephen
Maurer, and Andrej Sali
Sponsors
SAMSI, Duke Global Health, Duke Center for Bioinformatics and Computational Biology
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REGISTRATION
Registration information, including requests for financial support, should be submitted as soon as possible. ONLINE REGISTRATION IS REQUIRED. The registration deadline is MAY 13, 2005.� In order to ensure your registration is correct, we ask that you:
refresh/reload the registration page to ensure you have all updates
type in your information (cutting and pasting will distort the information we receive)
make any clarifications/corrections, in the Special Requests section
click the submit button only once
PRELIMINARY SCHEDULE
Sunday -- May 22, 2005
Radisson Hotel RTP, Room H (3rd Floor)
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8:30-9:00 AM |
Registration and Continental Breakfast � |
9:00-9:15 AM |
Welcome and Introduction Jim Berger, Director of SAMSI
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9:15-9:30 AM |
Collective Intelligence Tom Kepler, Duke University Medical Center
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9:30-10:30 AM |
The Tropical Disease Initiative' Stephen Maurer, University of California Berkeley
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10:30-10:45 AM |
Coffee Break � |
10:45-11:30 AM |
The Science of the Tropical Disease Iniative Marc Marti-Renom, University of California San Francisco
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11:30-12:45 PM |
Lunch
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12:45-1:35 PM |
The Malaria Capers Bob Desowitz, University of North Carolina
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1:35-2:25 PM |
Genome-Wide Inferences of Recombination, Positive and Negative Selection in the Agent of Malaria, Plasmodium Falciparum -- Towards a Malaria Hapmap Philip Awadalla, North Carolina State University
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2:25-2:40 PM |
Coffee Break
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2:40-3:30 PM |
Proteomics for Malaria Drug and Vaccine Target Discovery Tim Haystead, Duke University
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3:30-4:20 PM |
PlasmoDB: The Plasmodium Genome Resource Jessica Kissinger, University of Georgia
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4:20-5:10 PM |
Utilizing the Plasmodium Falciparum Genome to Combat Malaria Raphael Isokpehi, Jackson State University
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5:10-6:00 PM |
Future Direction for Malaria Research Victoria McGovern, Burroughs-Wellcome Foundation
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6:00 PM |
Closing Remarks Workshop Organizers |
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Monday -- May 23, 2005
Radisson Hotel RTP, Room H (3rd Floor)
8:30-9:00 AM |
Registration and Continental Breakfast � |
9:00-10:45 AM |
Legal and Social Aspects of Malaria Vaccine Development
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10:45-11:00 AM |
Coffee Break � |
11:00-12:45 PM |
Legal and Social Aspects (continued)
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12:45-2:00 PM |
Lunch
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2:00-3:45 PM |
Scientific and Technical Aspects of Malaria Vaccine Development
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3:45-4:00 PM |
Coffee Break
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4:00-5:45 PM |
Scientific and Technical Aspects (continued)
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5:45-6:00 PM |
Closing Remarks |
Tuesday -- May 24, 2005
Radisson Hotel RTP, Room H (3rd Floor)
8:30-9:00 AM |
Registration and Continental Breakfast � |
9:00-10:45 AM |
Legal and Social Aspects of Malaria Drug Development
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10:45-11:00 AM |
Coffee Break � |
11:00-12:45 PM |
Legal and Social Aspects (continued)
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12:45-2:00 PM |
Lunch
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2:00-3:45 PM |
Scientific and Technical Aspects of Malaria Drug Development
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3:45-4:00 PM |
Coffee Break
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4:00-5:45 PM |
Scientific and Technical Aspects (continued)
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5:45-6:00 PM |
Closing Remarks |
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� 2005, Statistical and Applied Mathematical Sciences Institute. All rights reserved.
Last updated on , 16 Sep 2004 19:48:14 GMT.
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